- Preheat the oven to 400°F and place a wire rack on top of a rimmed baking sheet and spray with nonstick spray and set aside. 
- Slice the top off of the jalapeños and carefully remove the seeds inside. Be sure to use gloves when working with jalapeños. - 12 large jalapeños 
- Combine the softened cream cheese with shredded cheddar cheese, brisket, and chili powder. Mix thoroughly. - 8 ounces cream cheese, 4 ounces cheddar cheese block, 2 cups finely chopped leftover beef brisket, ½ tablespoon chili powder 
- Add to a gallon-sized ziplock bag and cut off the corner to make a piping bag. Fill each jalapeño with the mixture. 
- Wrap each jalapeno with a strip of bacon. - 12 slices bacon 
- Place onto the prepared wire rack-lined baking sheet and bake for 10 minutes on the center rack. 
- Turn over and bake for another 10 minutes. 
- Remove jalapenos from the oven and brush with bbq sauce. Turn the broiler on low. - ¼ cup bbq sauce 
- Place the jalapenos 6” under the broiler for 2 minutes, keeping a close eye on them to make sure they don't burn. 
- Remove from the oven and let cool before serving.